An AlphaSeq Dataset of Antibody-Antigen Interactions for SARS-CoV-2

To support protein representation learning, we published two datasets containing quantitative binding scores of scFv-format antibodies against a SARS-CoV-2 target peptide collected via an AlphaSeq assay. Each dataset, associated license and descriptions are included in each subdirectory.

antibody_dataset_1: Contains the initial AlphaSeq Antibody Dataset. Please refer to our Data Descriptor Paper for additional information.

antibody_dataset_2: Contains antibodies designed using a machine learning framework and empirically measured. Please refer to our paper "Machine Learning Optimization of Candidate Antibodies Yields Highly Diverse Sub-nanomolar Affinity Antibody Libraries"  for additional information.